Author

Sandra Tavares

i3S - Instituto de Investigação e Inovação em Saúde, Universidade do PortoORCID 0000-0003-3055-914XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Organism:Drosophila· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Assay:metabolomics· 1 Assay:proteomics· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Florence JanodyiD· 2 shared Ana Marques· 1 shared Ana Rita Araujo· 1 shared Andreia G. Silva· 1 shared Anna Verena TaubenbergeriD· 1 shared Anne-Marie FortieriD· 1 shared Antoine A KhaliliD· 1 shared Bruno CavadasiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCancer Biology

Florence JanodyORCID

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Author profile →

2 papers

Recent·Most cited

Multi-omics analysis of TNBC organoids identifies phosphorylation of the membrane trafficking machinery as a key event associated with FER-mediated invasion

Carolien Elshout, Goncalo Mota, Joana Cunha, Sara Largher, Paula Sobrevals Alcaraz, Andreia G. Silva, Bruno Cavadas, Peter D. Haughton, Tuyet Nguyen, Robert M. van Es, Bruno S. Monteiro, Ana Rita Araujo, Ana Marques, Marta Teixeira Pinto, Maria Peixoto, , Sandra Tavares

The paper identifies phosphorylation of membrane trafficking regulators, particularly SEC16A, as key to FER-mediated invasion in TNBC organoids.

bioRxiv · Dec 21, 2025 · PreprintCancer Biology

Prior to Undergoing Epithelial to Mesenchymal Transition, Premalignant Cells Transiently Increase Tensile Forces at Cell-Cell and Cell-Matrix Adhesions

Lídia Dornelas de Faria, Carine M Gonçalves, Inês Fidalgo, Carla S. Lopes, Vanessa Rodrigues, Maria M. Azevedo, Paula Sampaio, Sandra Tavares, Vaibhav Mahajan, Anna Verena Taubenberger, Florence Janody

The paper shows that premalignant cells increase tensile forces at cell-cell and cell-matrix adhesions before losing them, promoting proliferation and malignant transformation.

bioRxiv · Jul 5, 2025 · PreprintCancer Biology