Pauliina Damdimopoulou

This paper creates an integrated multimodal atlas of the female reproductive system across the lifespan, identifying cell types and linking them to gynaecological pathologies.

The paper uses multimodal single-cell profiling to show how puberty and chemotherapy affect pediatric ovarian tissue, identifying vulnerabilities and a potential biomarker.

This study creates a single-nuclei transcriptomic atlas of skeletal muscle in women with PCOS, identifying cell-type-specific dysregulation and therapeutic targets.

This study examines how human ovarian cortical and medullary cells respond to acute X-ray exposure, finding transcriptomic shifts and impaired cell-cell adhesion.

This study develops and characterizes 3D models of human ovarian primary cells using Biosilk scaffolds, showing they maintain key cell types and form a hypoxic core.

This study shows that phthalate monoesters alter membrane fluidity and disrupt cell-cell contacts in endometrial stromal cells.

The paper identifies a conserved DNA motif bound by PLAG1 that regulates zygotic genome activation in mice and humans, affecting early embryo development.

The paper identifies EDC mixtures linked to adverse health outcomes and shows they disrupt gene regulatory networks in vitro and in vivo.