On-demand, cell-free biomanufacturing of conjugate vaccines at the point-of-care
Jessica C. Stark, Thapakorn Jaroentomeechai, Tyler D. Moeller, Jasmine M. Hershewe, Katherine F. Warfel, Bridget S. Moricz, Anthony M. Martini, Rachel S. Dubner, Karen J. Hsu, Taylor C. Stevenson, Bradley D. Jones, Matthew P. DeLisa, Michael C. Jewett
This paper develops a portable, freeze-dried system for producing conjugate vaccines at the point-of-care, showing higher antibody responses in mice compared to traditional methods.
Science Advances · Feb 3, 2021Peer-reviewedSynthetic Biology