Thapakorn Jaroentomeechai

The paper describes methods to make a membrane-bound glycosyltransferase water-soluble for easier study and application in synthetic glycobiology.

This study identifies that Siglec-7 and -15 recognize repeated clustered sulfo-sialo O-glycan motifs on specific O-glycoproteins, enhancing selectivity through multivalent interactions.

This study identifies biantennary N-glycans as receptors for MARTX toxins in Vibrio vulnificus, showing their role in pathogenesis and broad cell targeting.

The paper describes a method to isolate full-length IgG antibodies from combinatorial libraries in E. coli using a bifunctional antigen substrate for selection.

This paper introduces a method to construct and analyze neoglycoproteins by systematically modifying glycosylation sites in proteins and assessing the effects of glycan addition.

This paper introduces AddVax, a method to decorate bacterial outer membrane vesicles with biotinylated antigens to create vaccines, showing strong immune responses in mice.

This paper develops a portable, freeze-dried system for producing conjugate vaccines at the point-of-care, showing higher antibody responses in mice compared to traditional methods.

This paper presents a cell-free platform for synthesizing active oligosaccharyltransferases (OSTs) and demonstrates its ability to produce and test multiple OSTs for glycosylation reactions.

The paper describes a pipeline for studying and engineering single-subunit oligosaccharyltransferases (ssOSTs) using in vivo and in vitro methods.