Samuel Kohtala

This study shows that nitrous oxide increases cortical activity, alters wake-sleep oscillations, and produces antidepressant-like effects in mice, similar to ketamine.

This study shows that antidepressants activate TrkB receptors through physiological changes like hypothermia and reduced energy expenditure, not just pharmacological action.

This study shows that isoflurane anesthesia produces antidepressant-like effects in rodents by activating TrkB signaling and related molecular pathways.