Rui Guan

This study identifies YBX3 as an oncoprotein in mesothelioma that drives cell proliferation through SLC7A5/LAT1-mediated amino acid uptake and shows JPH203 as a potential therapeutic agent.

The paper identifies the core microbiota of terrestrial microalgae and shows environmental factors and microbe-microbe interactions shape its structure at lower taxonomic levels.

The paper shows that many soil bacteria depend on metabolite supplementation from other community members, revealing widespread cross-feeding in soil microbial communities.

This study investigates the off-target antibacterial effects of 1076 industrial and agricultural chemicals on 22 human gut bacteria, revealing 588 previously unreported interactions.

This study shows human gut bacteria can accumulate PFAS, with some species like Bacteroides uniformis accumulating them to high concentrations, and identifies mechanisms involving transmembrane transport and efflux pumps.

This study examines how bacterial proteomes and metabolomes change in response to interspecies interactions in gut microbiota co-cultures, revealing extensive molecular reorganization and emergent metabolic pathways.

The paper shows how species in gut bacterial communities can survive or go extinct based on resource availability and metabolic interactions, identifying emergent survival and community-driven extinctions.