Author

Logan Brooks

GenentechORCID 0000-0003-0877-4978Unclaimed ORCID profile · follow to get notified of new preprints

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:simulation· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrew Goetz· 1 shared Bartosz CzechiD· 1 shared Darlene Dela Cruz· 1 shared Eva LiniD· 1 shared Frances Shanahan· 1 shared Luca GerosaiD· 1 shared Purushottam D. DixitiD· 1 shared Rana M Mroue· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperSystems Biology

Andrew Goetz

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1 paper

Recent·Most cited

Systems BiologyCancersPeer-reviewedAug 22, 2024

Computational modeling of drug response identifies mutant-specific constraints for dosing panRAF and MEK inhibitors in melanoma

Andrew Goetz, Frances Shanahan, Logan Brooks…·Luca Gerosa

This study uses computational modeling and preclinical data to identify optimal dosing strategies for panRAF and MEK inhibitors in melanoma, revealing distinct dose requirements based on NRAS vs BRAF mutations.

3 citations

humanbulk RNA-seq

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