Author

Fred Bunz

Johns Hopkins UniversityORCID 0000-0003-0878-1553Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Aditya Pandya· 1 shared Sheri Li· 1 shared Vinod Jaskula-RangaiD· 1 shared Yumi JangiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 3 mutual co-author links

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1 shared paperMolecular Biology

Aditya Pandya

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintSep 28, 2026

Plasmid architecture determines the stability of inverted terminal repeats in adeno-associated virus vectors

Vinod Jaskula-Ranga, Sheri Li, Aditya Pandya, Fred Bunz

The paper identifies position-dependent ITR instability in AAV plasmids and develops a stable rAAV vector with full-length native ITRs.

DOI 10.64898/2026.09.24.753884

DNA methylationwhole-genome sequencing

𝕏 PostBluesky

Cancer BiologyPathogensPeer-reviewedFeb 2, 2025

Dynamic modulation of IRE1α-XBP1 signaling by adenovirus

Yumi Jang, Fred Bunz

This study shows that adenovirus serotype 5 modulates IRE1α-XBP1 signaling by activating IRE1 but blocking XBP1s production, revealing a novel antiviral mechanism evaded by the virus.

DOI 10.3390/pathogens14020132

humanexperimental assay

𝕏 PostBluesky