Author

Runze Shen

The University of Texas MD Anderson Cancer CenterORCID 0000-0003-0892-9845Unclaimed ORCID profile · follow to get notified of new preprints

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Molecular Biology· 1

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Approach:experimental assay· 1

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Andy ArvaiiD· 1 shared Ashok R. VenkitaramaniD· 1 shared Chi-Lin TsaiiD· 1 shared John A. TaineriD· 1 shared Katharina SchlacheriD· 1 shared Li Ren KongiD· 1 shared Michael A. Longo· 1 shared Miyoung Lee· 1 shared

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Andy ArvaiORCID

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1 paper

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Molecular BiologyMolecular CellPeer-reviewedJun 1, 2025

BRCA2 C-terminal clamp restructures RAD51 dimers to bind B-DNA for replication fork stability

Michael A. Longo, Syed Moiz Ahmed, Yue Chen…·Katharina Schlacher

This study reveals how the BRCA2 C-terminal domain reshapes RAD51 dimers to bind B-DNA, promoting replication fork stability over homology-directed repair.

14 citations

experimental assay

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