Mikaël Mazighi

This study shows that neutrophil extracellular traps (NETs) inhibit fibrinolysis during intravenous thrombolysis in acute ischemic stroke by sequestering tPA and plasminogen, and that DNase 1 can enhance thrombolysis by removing NETs.

This study shows that dural venous stenoses impair lymphatic drainage and brain fluid clearance, and that restoring venous flow can improve clearance in a mouse model.