Vincenzo Mastrolia

The paper shows that in vivo modulation of network activity changes the nanoscale organization of axo-axonic synapses, reducing Gephyrin SSD volume and weakening synaptic contacts.

The paper shows that excitatory and inhibitory synapses are tightly balanced along dendrites in developing hippocampal neurons, with this balance declining as the neurons mature.

This study shows that Pyk2 in the dorsal hippocampus is crucial for specific spatial memory tasks and synaptic plasticity, with effects dependent on experimental protocols.