Guilherme Neves

The paper shows that increased HCN1 activity in excitatory neurons causes excessive network bursting in Dravet syndrome, suggesting HCN1 as a therapeutic target.

The paper introduces a software workflow for correlating optical and electron microscopy data to target specific regions of interest for electron tomography analysis.

The paper shows that excitatory and inhibitory synapses are tightly balanced along dendrites in developing hippocampal neurons, with this balance declining as the neurons mature.

This study shows that TDP-43G298S mutations in human iPSC-derived motor neurons alter axon initial segment structure and neuronal excitability at different developmental stages.

The paper identifies multi-synaptic boutons (MSBs) in CA1 hippocampal connections, which show reduced variation in synaptic properties and may support network synchrony.

This study shows that homeostatic plasticity rules govern axo-axonic synapse formation in chandelier cells, with activity changes during specific developmental windows altering synaptic connectivity.

The paper shows that apoptosis of inhibitory interneurons in the cortex is regulated by neuronal activity and can be modulated to adjust their numbers.