Yingying Zhang

The paper identifies a sequence-structure dual-match mechanism in IS110 transposons that enhances target recognition fidelity beyond RNA-DNA base pairing.

This paper shows that arginine di-methylation of RIPK3 by PRMT5 prevents necroptosis in intestinal epithelial cells, maintaining homeostasis and preventing disease.

The paper identifies the Z-RNA-ZBP1 axis as a driver of Tau-mediated neurodegeneration and shows that ZBP1 inhibition can alleviate cognitive deficits in Tau-transgenic mice.

DeepRTAlign improves retention time alignment for large cohort LC-MS data, enhancing identification sensitivity without compromising quantitative accuracy and enabling predictive modeling for hepatocellular carcinoma recurrence.

This paper describes a method to generate blastocyst-like structures from human pluripotent stem cells and shows they resemble blastocysts in morphology and transcriptome.