Author

Logan J. Blaine

Harvard UniversityORCID 0000-0003-0937-9216Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Cheng‐Zhong ZhangiD· 1 shared David S. PellmaniD· 1 shared Lili Sun· 1 shared Mitchell J. WeissiD· 1 shared Mitchell L. LeibowitziD· 1 shared Phillip A. DoerfleriD· 1 shared Stamatis PapathanasiouiD· 1 shared Yu YaoiD· 1 shared

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2021-2021 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperGenetics

Cheng‐Zhong ZhangORCID

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1 paper

Recent·Most cited

GeneticsNature GeneticsPeer-reviewedApr 12, 2021

Chromothripsis as an on-target consequence of CRISPR-Cas9 genome editing

Mitchell L. Leibowitz, Stamatis Papathanasiou, Phillip A. Doerfler…·David S. Pellman

This paper shows that CRISPR-Cas9-induced DNA breaks can lead to chromothripsis, a catastrophic chromosomal rearrangement, which is an on-target toxicity in genome editing.

585 citationstop 1%

humanwhole-genome sequencing

𝕏 PostBluesky