Author

Stamatis Papathanasiou

Institute of Molecular BiologyORCID 0000-0001-6969-044XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Aditi GnanasekariD· 1 shared Alastair Hamilton· 1 shared Alexander Herrmann· 1 shared Alexander KukaleviD· 1 shared Ana PomboiD· 1 shared Andrea VenturaiD· 1 shared Ann-Sophie Hollinger· 1 shared Annika LehmanniD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Aditi GnanasekarORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

DNA damage at Lamina-Associated Domains triggers nuclear envelope reorganization and chromatin detachment to prevent nuclear envelope blebbing and genome instability.

Diana Rubio-Contreras, Sylvain Audibert, Joanna Fernández, Ruxandra A. Lambuta, Nikoleta Pateraki, Karen Meaburn, Jack Wootton, Raquel Carreira, Nishita Parnandi, Ramón González‐Méndez, Simon J. Boulton, Zuza Kozik, Stamatis Papathanasiou, Evi Soutoglou

bioRxiv · Oct 27, 2026 · PreprintCell Biology

Extrachromosomal DNA micronucleation constrains tumour fitness andimproves patient survival

Lotte Brückner, Robin Xu, Jun Tang, Aditi Gnanasekar, Alexander Herrmann, Ivy Tsz-Lo Wong, Shu Zhang, Fengyu Tu, Madison Pilon, Alexander Kukalev, Katharina Pardon, Olga Alexandra Sidorova, Joshua Atta, Qinghao Yu, Giulia Montouri, , Anton George Henssen

This study shows that ecDNA mis-segregation leads to micronuclei formation, reduced oncogene transcription, and improved patient survival in neuroblastoma.

bioRxiv · Apr 15, 2025 · PreprintCancer Biology

Chromothripsis as an on-target consequence of CRISPR-Cas9 genome editing

Mitchell L. Leibowitz, Stamatis Papathanasiou, Phillip A. Doerfler, Logan J. Blaine, Lili Sun, Yu Yao, Cheng‐Zhong Zhang, Mitchell J. Weiss, David S. Pellman

This paper shows that CRISPR-Cas9-induced DNA breaks can lead to chromothripsis, a catastrophic chromosomal rearrangement, which is an on-target toxicity in genome editing.

Nature Genetics · Apr 12, 2021Peer-reviewedGenetics