Author

Marc C. Gielen

Centre National de la Recherche ScientifiqueORCID 0000-0003-0941-4325Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

François BontemsiD· 1 shared Gabriel AyméiD· 1 shared Gabrielle Dejean de la Bâtie· 1 shared Gérard Pehau‐ArnaudetiD· 1 shared Marie S. PrevostiD· 1 shared Nathalie BariloneiD· 1 shared Patrick EnglandiD· 1 shared Pierre J. LafayeiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

François BontemsORCID

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1 paper

Recent·Most cited

NeuroscienceNature CommunicationsPeer-reviewedSep 25, 2023

An original potentiating mechanism revealed by the cryoEM structures of the human α7 nicotinic receptor in complex with nanobodies

Marie S. Prevost, Nathalie Barilone, Gabrielle Dejean de la Bâtie…·Pierre‐Jean Corringer

The paper solves cryo-EM structures of human α7 nicotinic receptor nanobody complexes, revealing E3's mechanism of inducing active or desensitized conformations through a N-linked sugar moiety.

25 citations

humanprotein structure

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