Author

Nathalie Barilone

Centre National de la Recherche ScientifiqueORCID 0000-0003-0373-7262Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Gabriel AyméiD· 2 shared Gabrielle Dejean de la Bâtie· 2 shared Marie S. PrevostiD· 2 shared Pierre J. LafayeiD· 2 shared Pierre‐Jean CorringeriD· 2 shared Stéphanie PonsiD· 2 shared Uwe MaskosiD· 2 shared Ákos NemecziD· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersNeuroscience

Gabriel AyméORCID

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2 papers

Recent·Most cited

NeuroscienceNature CommunicationsPeer-reviewedSep 25, 2023

An original potentiating mechanism revealed by the cryoEM structures of the human α7 nicotinic receptor in complex with nanobodies

Marie S. Prevost, Nathalie Barilone, Gabrielle Dejean de la Bâtie…·Pierre‐Jean Corringer

The paper solves cryo-EM structures of human α7 nicotinic receptor nanobody complexes, revealing E3's mechanism of inducing active or desensitized conformations through a N-linked sugar moiety.

25 citations

humanprotein structure

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NeuroscienceCellular and Molecular Life SciencesPeer-reviewedMay 25, 2023

Generation of nanobodies acting as silent and positive allosteric modulators of the α7 nicotinic acetylcholine receptor

Qimeng Li, Ákos Nemecz, Gabriel Aymé…·Pierre‐Jean Corringer

This paper describes the generation of nanobodies that act as silent and positive allosteric modulators of the α7 nicotinic acetylcholine receptor, with distinct functional properties.

13 citations

humanexperimental assay

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