Author

Charles N. J. Ravarani

MRC Laboratory of Molecular BiologyORCID 0000-0003-0952-3396Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 2 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Assay:protein structure· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Hannes A. BaukmanniD· 2 shared Justin L. Cope· 2 shared Marco Florian SchmidtiD· 2 shared Ala TrusinaiD· 1 shared Alexander R. E. C. Schwinges· 1 shared Colin BannardiD· 1 shared Erwin P. BöttingeriD· 1 shared Joern E. Klinger· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Hannes A. BaukmannORCID

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3 papers

Recent·Most cited

Genetic & Genomic MedicineFrontiers in GeneticsPeer-reviewedOct 20, 2021

Interaction-based feature selection algorithm outperforms polygenic risk score in predicting Parkinson's Disease status

Jörn Klinger, Charles N. J. Ravarani, Hannes A. Baukmann…·Marco Florian Schmidt

The paper presents an interaction-based feature selection algorithm that outperforms polygenic risk scores in predicting Parkinson's Disease status using the PPMI dataset.

10 citations

humanwhole-genome sequencing

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Genetic & Genomic MedicinemedRxivPreprintMay 18, 2021

Neutrophils cause critical illness in COVID-19 and reveal CDK6 inhibitors as potential treatment

Hannes A. Baukmann, Justin L. Cope, Charles N. J. Ravarani…·Marco Florian Schmidt

The paper identifies high neutrophil count as a causal trait in severe COVID-19 and suggests CDK6 inhibitors as potential treatment.

2 citations

humanbulk RNA-seq

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Systems BiologyMolecular Systems BiologyPeer-reviewedApr 1, 2019

The fitness cost and benefit of phase separated protein deposits

Natalia Sánchez de Groot, Marc Torrent, Charles N. J. Ravarani…·M. Madan Babu

The paper quantifies the fitness costs and benefits of protein deposit formation via phase separation in yeast, showing environmental and functional demands influence fitness outcomes and generate phenotypic variability.

16 citations

yeastprotein structure

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