Developmental BiologybioRxivPreprint
Knockout of cardiolipin synthase disrupts postnatal cardiac development by inhibiting the maturation of mitochondrial cristae
Mindong Ren, Xu Yang, Colin K. L. Phoon…·Michael Schlame
This study shows that cardiolipin is essential for postnatal cardiac maturation by enabling mitochondrial cristae to accumulate OXPHOS proteins and protect them from degradation.
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