Author

Sara Martínez-Martínez

Spanish National Centre for Cardiovascular ResearchORCID 0000-0003-0973-3406Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Juan Miguel RedondoiD· 2 shared Alberto Forteza· 1 shared Álvaro Alfayate· 1 shared Amanda Leal-Zafra· 1 shared Ana Isabel Torralbo· 1 shared Andrea GualaiD· 1 shared Ángel Colmenar· 1 shared Antonio Rochano-OrtiziD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersPathology

Juan Miguel RedondoORCID

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2 papers

Recent·Most cited

PathologyPLoS BiologyPeer-reviewedMay 14, 2025

Phosphatase-independent activity of smooth-muscle calcineurin orchestrates a gene expression program leading to hypertension

Paula Sofía Yunes-Leites, Yilin Sun, Sara Martínez-Martínez…·Miguel R. Campanero

This study shows that smooth-muscle calcineurin, independent of its phosphatase activity, drives a gene expression program that causes hypertension.

5 citations

mousebulk RNA-seq

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Molecular BiologybioRxivPreprintMay 31, 2024

Integrated Stress Response Triggered by Excessive Glycosylation Drives Thoracic Aortic aneurysm

Antonio Rochano-Ortiz, Irene San Sebastián-Jaraba, Carmen Zamora…·Jorge Oller

This study identifies the HBP-ISR axis as a driver of thoracic aortic aneurysm in Marfan Syndrome, showing that targeting this pathway can reverse aortic dilation in mice and is associated with human TAAD.

1 citation

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