David N. Arnosti

This study uses CRISPRi to compare Rbf1 and Rbf2 paralogs in Drosophila, revealing their distinct and context-dependent roles in gene repression.

The paper investigates the functional role of the unstructured C-terminal domain (CTD) of CtBP proteins by comparing isoforms with and without the CTD in Drosophila, showing context-dependent repression activity.

The paper investigates the regulatory mechanisms of the Drosophila insulin-like receptor gene, revealing complex enhancer interactions and the role of ecdysone receptor in long-range repression.

This study investigates the functional diversification of retinoblastoma proteins in Drosophila, showing that Rbf2 regulates distinct gene sets and has specialized roles in reproductive development.

The paper uses machine learning to predict enhancers in Drosophila, finding that no single factor is necessary and spatial-temporal features improve classification.