Author

Alisha M. Block

University of MinnesotaORCID 0000-0003-0987-9181Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1

Frequent Co-Authors

Anna D. TischleriD· 2 shared Dylan W. WhiteiD· 1 shared Leanne ZhangiD· 1 shared Michael NiederweisiD· 1 shared Parker C. Wiegert· 1 shared Rashmi Ravindran NairiD· 1 shared Sarah B. Namugenyi· 1 shared Virginia MeikleiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 22 mutual co-author links

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2 shared papersMicrobiology

Anna D. TischlerORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintSep 26, 2026

Mycobacterium tuberculosis requires riboflavin biosynthesis for survival in the host

Alisha M. Block, Sarah B. Namugenyi, Anna D. Tischler

This study shows that Mycobacterium tuberculosis needs riboflavin biosynthesis for survival during all stages of infection, suggesting it as a drug target.

DOI 10.64898/2026.09.25.754416

mousebulk RNA-seq

𝕏 PostBluesky

MicrobiologymBioPeer-reviewedJan 30, 2026

The Mycobacterium tuberculosis ESX-5 secretion system enables carbon source utilization and growth in mice

Alisha M. Block, Rashmi Ravindran Nair, Virginia Meikle…·Anna D. Tischler

This study shows that the M. tuberculosis ESX-5 secretion system is critical for growth on specific carbon sources, survival in macrophages, and replication in mice, suggesting it is a key virulence factor.

4 citationstop 1%

mouseexperimental assay

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