Anna D. Tischler

This study shows that Mycobacterium tuberculosis needs riboflavin biosynthesis for survival during all stages of infection, suggesting it as a drug target.

This paper identifies that lactate and phosphate together cause cytoplasmic acidification and reduced proton motive force, leading to growth arrest in Mycobacterium tuberculosis at acidic pH.

This study shows that the M. tuberculosis ESX-5 secretion system is critical for growth on specific carbon sources, survival in macrophages, and replication in mice, suggesting it is a key virulence factor.

This study shows that M. tuberculosis uses the Pst/SenX3-RegX3 system to regulate ESX-5 secretion, which is critical for evading host immunity.