Jérôme Savocco

This study investigates how Rad55-Rad57 and Srs2 regulate homology search in yeast by controlling Rad51-ssDNA filament stability and coordination.

The paper identifies condensin-dependent loop extrusion and roadblocks in S. cerevisiae, showing their role in homology search during DNA repair.

This paper investigates the mechanism of homology search expansion during DNA break repair, revealing how chromatin structure, NPF stiffening, and resection drive genome-wide search.

This study shows cohesin promotes cis dsDNA over-sampling during homology search in yeast by blocking cohesin progression and enabling loop expansion-coupled scanning.