Author
University of California, Los AngelesORCID 0000-0003-0994-7658Unclaimed ORCID profile · follow to get notified of new preprints
7 papers
Recent·Most cited
Terence W. Li, Justin Langerman, Cuining Liu…·Kathrin Plath
This study examines epigenomic and spatial changes during human reprogramming, finding distinct molecular and spatial patterns in productive versus unsuccessful trajectories.
Colette Lafontaine Picard, Lucia Ichino, Tyler J. Buckley…·Steven E. Jacobsen
The paper reveals an antagonistic epigenetic mechanism in Arabidopsis pollen where MBD5/6 repress methylated loci while MBD7 promotes demethylation and transcriptional activation.
Zeyuan Johnson Chen, Sankha Subhra Das, Asha Kar…·Päivi Pajukanta
The paper characterizes the epigenomic and 3D genomic landscape of human subcutaneous adipose tissue at the cell-type level and links epigenomic variation to abdominal obesity risk.
Katherine W. Eyring, Cuining Liu, Nasser Elhajjaoui…·Chongyuan Luo
The paper presents a single-cell DNA methylation and transcriptomics analysis of ASD, identifying cell type-specific methylation changes and age-related effects in the brain.
Terence Li, Marcus Alvarez, Cuining Liu…·Noah Zaitlen
The paper evaluates demultiplexing methods for joint snRNA/snATAC experiments under ambient contamination and introduces a new metric to assess their performance.
Guanglin Zhang, Graciel Diamante, In Sook Ahn…·Xia Yang
This study shows T4 treatment alters cell-type specific genes, pathways, and networks in hippocampus and frontal cortex after mTBI, reversing mTBI-affected genes and pathways.
Matthew G. Heffel, Jingtian Zhou, Yi Zhang…·Chongyuan Luo
The paper investigates epigenomic and 3D chromatin conformation changes in human frontal cortex and hippocampus development using sn-m3C-seq, finding distinct chromatin conformations in neurons and glial cells and linking risk variants to regulatory regions.