GeneticsThe Journal of PathologyPeer-reviewed
IFT-A deficiency in juvenile mice impairs biliary development and exacerbates ADPKD liver disease
Wei Wang, Tana S. Pottorf, Henry H. Wang…·Pamela Vivian Tran
This study shows that Thm1 deletion in juvenile Pkd2 mice worsens biliary development and PLD, while adult Thm1 deletion has no effect, highlighting distinct roles of IFT-A and IFT-B in liver disease.
18 citations