Paula Maglio Cauhy

This paper introduces coppaFISH 3D and CASTalign to enable transcriptomic identification of thousands of in vivo recorded neurons at scale.

This study uses mouse models with tau mutations to show two distinct pathogenic mechanisms in tauopathies, with different progression patterns and responses to amyloid.

The paper identifies tau filaments within extracellular vesicles from Alzheimer's disease patients using mass spectrometry and cryo-electron microscopy.