Moriah Rene Beck

This paper identifies conserved basic residue clusters in the Ig3 domain of myopalladin (MYPN) critical for actin binding and bundling, showing that cardiomyopathy-associated mutations disrupt these interactions and lead to abnormal subcellular localization.

This study investigates how the length and composition of an intrinsically disordered linker in Palladin affect its actin binding and bundling capabilities.

This paper determines the structure of the palladin-actin complex using crosslinking, docking, NMR, and SAXS, revealing how palladin stabilizes F-actin at the interface between two actin monomers.

The paper introduces OglyPred-PLM, a model using ProtT5-XL-UniRef50 embeddings to predict human O-linked glycosylation sites, outperforming existing methods on a benchmark dataset.