Author

Matthieu Genais

Centre National de la Recherche ScientifiqueORCID 0000-0003-1004-865XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Approach:deep learning· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:statistical model· 1 Research Focus:trajectory inference· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Raphaël MouradiD· 2 shared Vincent RocheriD· 2 shared Aline MarnefiD· 1 shared Aude Guénolé· 1 shared Coline ArnouldiD· 1 shared Dipti Vinayak Vernekar· 1 shared Elissar Nassereddine· 1 shared Gaëlle LegubeiD· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersBioinformatics

Raphaël MouradORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintJul 22, 2020

DeepG4 : A deep learning approach to predict active G-quadruplexes from DNA

Vincent Rocher, Matthieu Genais, Elissar Nassereddine, Raphaël Mourad

DeepG4 accurately predicts active G-quadruplexes in DNA using a convolutional neural network, identifying key motifs and showing their impact on transcription and chromatin.

3 citations

DNA methylationdeep learning

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Molecular BiologybioRxivPreprintMay 13, 2020

BLM-dependent Break-Induced Replication handles DSBs in transcribed chromatin upon impaired RNA:DNA hybrids dissolution.

S Cohen, Aude Guénolé, Aline Marnef…·Gaëlle Legube

This study shows BLM promotes Homologous Recombination at DSBs in active chromatin but switches to Break-Induced Replication when R-loop dissolution is impaired, reducing cell viability.

3 citations

humanDNA methylation

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