Author

Aline Marnef

Centre National de la Recherche ScientifiqueORCID 0000-0002-7023-1360Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1 Research Focus:trajectory inference· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Aude Guénolé· 2 shared Coline ArnouldiD· 2 shared Gaëlle LegubeiD· 2 shared Marion AguirrebengoaiD· 2 shared Nadine PugetiD· 2 shared Vincent RocheriD· 2 shared Anne-Laure Finoux· 1 shared Benjamin Le Bozec· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersMolecular Biology

Aude Guénolé

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2 papers

Recent·Most cited

Molecular BiologyMolecular CellPeer-reviewedNov 20, 2025

Circadian PERIOD proteins regulate TC-DSB repair through anchoring to the nuclear envelope

Benjamin Le Bozec, Laure Guitton-Sert, Sarah Collins…·Gaëlle Legube

The paper identifies PERIOD proteins as regulators of TC-DSB repair by anchoring DSBs to the nuclear envelope, linking circadian rhythms to DNA repair mechanisms.

16 citationstop 4%

humanexperimental assay

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Molecular BiologybioRxivPreprintMay 13, 2020

BLM-dependent Break-Induced Replication handles DSBs in transcribed chromatin upon impaired RNA:DNA hybrids dissolution.

S Cohen, Aude Guénolé, Aline Marnef…·Gaëlle Legube

This study shows BLM promotes Homologous Recombination at DSBs in active chromatin but switches to Break-Induced Replication when R-loop dissolution is impaired, reducing cell viability.

3 citations

humanDNA methylation

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