Author

Michael M. Givertz

Brigham and Women's HospitalORCID 0000-0003-1012-7710Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Ake Tzu-Hui LuiD· 1 shared Alexander TyshkovskiyiD· 1 shared Amin HaghaniiD· 1 shared Friederike MartiniD· 1 shared Hao Zhou· 1 shared Jesse R. PoganikiD· 1 shared Stefan G. TulliusiD· 1 shared Steve HorvathiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperSystems Biology

Ake Tzu-Hui LuORCID

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1 paper

Recent·Most cited

Transplanted hearts assimilate the recipient's biological age

Jesse R. Poganik, Tomohisa Matsunaga, Alexander Tyshkovskiy, Ake Tzu-Hui Lu, Amin Haghani, Hao Zhou, Friederike Martin, Steve Horvath, Michael M. Givertz, Stefan G. Tullius, Vadim N. Gladyshev

DNA methylation clocks show heterochronic heart grafts shifting toward recipient age in syngeneic mice and 11 human recipients, while recipient mouse native heart, liver and blood show no consistent change.

bioRxiv · Sep 17, 2026 · PreprintSystems Biology✦ In-depth digest