Jimmy Kuang‐Hsien Hu

The paper shows that mitochondrial pyruvate transport and endocytosis regulate the cell jamming transition in epithelial tissues.

This paper introduces a framework to convert continuous neural network attributions into testable biological hypotheses using decision trees and language models, validated on single-cell omics data.

This study measures intracellular strain using microscopy and finds an inverse relationship between cytoplasmic and nuclear strains controlled by nucleo-cytoskeletal coupling.

The paper shows that cell morphology and nucleus size heterogeneity drive chromatin modification changes, affecting euchromatic and heterochromatic marks.

This paper introduces a method for high-resolution whole tissue imaging and automatic cell segmentation, demonstrating its application in studying epithelial bending in transgenic mice and catsharks.

This study maps the transcriptional landscape of developing mouse mandibular epithelium to identify key transcription factors and gene regulatory networks involved in oral epithelial patterning and organ specification.