GeneticsbioRxivPreprint
Genome-wide CRISPR screen reveals host genes that regulate SARS-CoV-2 infection
Jin Wei, Mia Madel Alfajaro, Ruth E. Hanna…·Craig B. Wilen
A genome-wide CRISPR screen with SARS-CoV-2 recovers ACE2 and Cathepsin L and nominates SWI/SNF, TGF-beta signalling and HMGB1 as pro-viral; pathway inhibitors blocked virus-induced death.
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