Molecular BiologybioRxivPreprint
OGG1 and MUTYH repair activities promote telomeric 8-oxoguanine induced cellular senescence
Mariarosaria De Rosa, Ryan P. Barnes, Prasanth R. Nyalapatla…·Patricia Lynn Opresko
The paper shows that OGG1 and MUTYH repair activities are required for telomeric 8-oxoguanine-induced cellular senescence, with their loss reducing senescence and telomere dysfunction.
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