Author
University of PittsburghORCID 0000-0001-7458-7359Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
3 papers
Recent·Most cited
Mariarosaria De Rosa, Theresa M. Heidenreich, Libby Childs…·Patricia Lynn Opresko
This study shows MUTYH prevents telomere shortening and genomic instability in cancer cells under chronic 8-oxoG damage by resolving BER intermediates.
Mariarosaria De Rosa, Ryan P. Barnes, Prasanth R. Nyalapatla…·Patricia Lynn Opresko
The paper shows that OGG1 and MUTYH repair activities are required for telomeric 8-oxoguanine-induced cellular senescence, with their loss reducing senescence and telomere dysfunction.
Ryan P. Barnes, Mariarosaria De Rosa, Sanjana A. Thosar…·Patricia Lynn Opresko
This study shows that telomeric 8-oxoguanine induces premature senescence without telomere shortening by causing replication stress and dysfunction.