Michael F. Schmid

This study uses cryo-EM and deep learning to reveal the sequential structural changes in human TRiC during ATP-induced ring closure, showing asymmetric subunit responses and coordinated domain movements.

The paper visualizes the nucleation, condensation, and propagation of β-tubulin folding in the chaperonin TRiC, showing a hierarchical process involving nonnative structures and TRiC subunits.

The paper introduces and analyzes Q-scores to assess the reliability of atomic coordinate models fitted to 3DEM maps, showing their correlation with map resolution and model quality.

The paper uses cryogenic electron tomography to redefine herpesvirus capsid assembly intermediates inside the cell nucleus by deriving atomic models and revealing structural heterogeneity in capsid components.

This study analyzes the factors affecting resolution in cryoET-STA for MmCpn, evaluating the cost-benefit of achieving high-resolution structures.

This study shows that mitochondrial repositioning and reorientation in Chlamydomonas reinhardtii under low CO2 conditions is regulated by CIA5 and supports CO2 concentrating mechanism function.

This paper introduces an unsupervised learning approach using coordinate networks to address the missing wedge problem in cryoET, improving reconstruction quality and reducing runtime.

This study uses cryoET and proteomics to identify mitochondrial and organelle abnormalities in HD models, showing potential for early diagnosis and therapy development.

This study uses cryo-electron tomography to reveal the molecular structures of two tubulin-based cytoskeleton structures in Toxoplasma gondii, showing their architecture and role in invasion.