Grigore D Pintilie

Q-score as a reliability measure for protein, nucleic acid, and small molecule atomic coordinate models derived from 3DEM density maps

The paper introduces and analyzes Q-scores to assess the reliability of atomic coordinate models fitted to 3DEM maps, showing their correlation with map resolution and model quality.

Complex Water Networks Visualized through 2.2-2.3 Angstrom Cryogenic Electron Microscopy of RNA

Two Tetrahymena ribozyme cryo-EM maps (2.2 and 2.3 Å) reveal cross-validated ordered waters and Mg2+ ions, plus reproducible diffuse solvent density resembling molecular dynamics water networks.

Cryo-ET reveals two major tubulin-based cytoskeleton structures in Toxoplasma gondii

This study uses cryo-electron tomography to reveal the molecular structures of two tubulin-based cytoskeleton structures in Toxoplasma gondii, showing their architecture and role in invasion.