Author

Yasutaka Motomura

RIKENORCID 0000-0003-1088-9985Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:scRNA-seq· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Kazuyo MoroiD· 2 shared Aki MinodaiD· 1 shared Alireza Ahmadi· 1 shared Ayaka Ichikawa NagasatoiD· 1 shared Chung-Chau HoniD· 1 shared Haitao WangiD· 1 shared Haruka YabukamiiD· 1 shared Hironobu FujiwaraiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersGenomics

Kazuyo MoroORCID

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2 papers

Recent·Most cited

GenomicsbioRxivPreprintNov 19, 2025

Epigenomic and transcriptomic germ-free ageing atlas reveals sterile inflammation as an intrinsic ageing feature

Ward Nijen Twilhaar, Jen-Chien Chang, Tommy W. Terooatea…·Aki Minoda

This study presents a single-cell epigenomic and transcriptomic atlas of aged mice under germ-free conditions, revealing sterile inflammation as an intrinsic ageing feature.

DOI 10.1101/2025.11.19.689100

mousescRNA-seq

𝕏 PostBluesky

Systems BiologybioRxivPreprintApr 18, 2023

Nuclear NFκB Activity Balances Purine Metabolism in Cellular Senescence

Sho Tabata, Keita Matsuda, Kenshiro Nagai…·Mariko Okada

This study shows that sustained NFκB activity promotes cellular senescence by altering purine metabolism and epigenetic regulation through IκB and A20 dysfunction.

1 citation

mousestatistical model

𝕏 PostBluesky