Seeding the meiotic DNA break machinery and initiating recombination on chromosome axes
Ihsan Dereli, Vladyslav Telychko, Frantzeskos Papanikos…·Attila Tóth
The paper identifies IHO1-HORMAD1 as essential for seeding the meiotic DSB machinery on chromosome axes, ensuring sufficient DSBs for homologous chromosome pairing in mice.