Jörg Großhans

This study identifies HSPB8's role in regulating CTP synthase filaments to link nucleotide metabolism and autophagy in tumors, showing that disrupting these filaments impairs tumor growth and correlates with poor patient survival.

The paper shows that E-cadherin junctions in Drosophila embryos mature during gastrulation, with increased levels and reduced mobility, controlled by Myo-II contractility, Rho signaling, and Src42A.

The paper studies nuclear movement in Drosophila embryos, showing collective cytoskeletal remodeling drives yo-yo-like nuclear drift during mitosis.

The paper describes an optochemical method to induce reversible cell contractions in vivo at single-cell resolution using Ca2+ bursts.

The paper shows the emergence of the subapical domain during the midblastula transition in Drosophila embryos is controlled by zygotic gene expression, not the nucleo-cytoplasmic ratio.

This paper introduces a cycle-consistent GAN for automated epithelial tissue segmentation without requiring image-mask pairs.

The paper introduces a method to create conditional motor protein mutants by inserting a protease cleavage site, demonstrating its use with Kinesin-5 in Drosophila embryos to reveal its interphase function in microtubule stabilization.

This study shows that Lamin Dm0 and Kugelkern suppress intestinal stem cell proliferation in Drosophila by inhibiting Jak/Stat signaling.

The paper identifies protein phosphatase V's role in controlling Twine levels to ensure timely cell cycle remodeling during the mid-blastula transition in Drosophila.