Fred Wolf

NeuroDisco provides optogenetic stimulation to neuronal cultures to reduce synchronized bursting and enable functional analysis of neuronal activity.

The paper identifies coordinated nanoscale spine remodeling linked to synaptic plasticity using in vivo long-term nanoscopy and data-driven generative models.

The paper shows that population coding in cortical neurons depends on precise physiological parameters, validated through experiments on mouse barrel cortex neurons.

This study uses multivariate transfer entropy to analyze real-time social information transfer during perceptual decision-making in dyadic interactions.

This study uses MINFLUX nanoscopy to map the nanoscale organization of proteins at inner hair cell synapses in mice, revealing nanocluster-based structures in active zones and postsynaptic densities.

This study investigates the developmental plasticity of cochlear inner hair cell ribbon synapses using live-cell imaging, revealing activity-dependent mechanisms in their structural maturation.

The paper examines single neuron diversity in primate visual cortical areas V1 and LPFC, finding differences in morphology, electrophysiology, and intrinsic bursting that may underlie functional specialization.

The paper shows that E-cadherin junctions in Drosophila embryos mature during gastrulation, with increased levels and reduced mobility, controlled by Myo-II contractility, Rho signaling, and Src42A.

The paper decomposes the dynamic gain function to attribute network-level encoding features to specific cell-level parameters in neurons and models.

The paper investigates how neuronal oscillations affect chaotic dynamics in cortical circuits, finding that oscillatory input increases chaotic measures at the network's resonance frequency.

The paper uses STED nanoscopy to show environmental enrichment sharpens synaptic nanoarchitecture dynamics and enhances synaptic precision.

The paper investigates how axonal ion channel properties affect ultrafast population coding in cortical neurons, finding that voltage sensitivity, not quantity or location, determines coding speed and high-frequency response.

The paper shows that prefrontal interneurons adjust their sensitivity to high-frequency oscillations based on background activity, enhancing gamma and ripple responses during slow brain states.

This study uses in vivo STED nanoscopy to show that dendritic spines undergo extensive remodeling over time, with both volatile and stable components, and this is exaggerated in a neurodegeneration model.

The paper describes an optochemical method to induce reversible cell contractions in vivo at single-cell resolution using Ca2+ bursts.

The paper shows that calcium accumulations in dendritic spines precede their removal by phagocytes in cortical inflammation, and blocking phagocyte activation prevents synapse loss.

The paper studies how transparency affects strategy success in an iterated Prisoner's Dilemma using evolutionary simulations, finding that WSLS dominates low/moderate transparency while Leader-Follower outperforms at maximal transparency.

This paper introduces a cycle-consistent GAN for automated epithelial tissue segmentation without requiring image-mask pairs.

The paper comments on a study that identifies two types of asynchronous activity in spiking neuron networks and discusses the implications for slow neural dynamics.