Huahui Ren

Genos-m is a foundation model for human-associated microbial genomes that outperforms existing models in gene-fitness prediction and community structure analysis.

The paper expands the gene catalog of mouse gut metagenomes by integrating new samples and genomes, increasing gene count and improving taxonomic and functional annotations.

This paper compares amplicon, hybrid capture, and metatranscriptomic sequencing methods for directly sequencing SARS-CoV-2 genomes from clinical samples, finding differences in bias, sensitivity, and accuracy.

This study identifies age-related sex differences in gut microbiota composition and functionality across two population cohorts, showing women have more diverse and stable microbiota than men, with sex differences diminishing in older adults.