Karsten Kristiansen

The paper proposes a molecular assessment strategy using transcriptomic and cytokine profiling to evaluate fetal bovine serum (FBS) performance, showing that molecular profiling is more reliable than geographical origin or CoA parameters.

This study uses complete genomes to model gut microbiome metabolic interactions, revealing ecological group dynamics linked to inflammatory bowel disease and improving disease diagnosis.

The paper presents a comprehensive compendium of fully circularized human gut bacterial genomes and reveals how mobile genetic elements drive functional diversity with therapeutic implications.

The paper introduces a spatial dissimilarity method to analyze single-cell and spatial transcriptomics data, identifying alternative splicing and allele-specific gene expression in various cell types.

The paper investigates how dual utilization of human milk oligosaccharides and dietary fibers influences gut microbiome selection during weaning.

CompleteBin improves short contig binning in complex microbial communities, recovering more complete genomes and novel genes, with applications in environmental metagenomics.

PepGo is a deep learning and tree search-based model for de novo peptide sequencing that outperforms existing methods by integrating Transformer networks with Monte Carlo Tree Search.

The paper investigates how host genetics and gut microbiota interact with parasite infections in Atlantic salmon, finding that cestode infections alter microbiota composition and host gene expression.

Chord improves doublet detection in scRNA-seq by combining multiple methods, showing higher accuracy and stability across different datasets.

The paper expands the gene catalog of mouse gut metagenomes by integrating new samples and genomes, increasing gene count and improving taxonomic and functional annotations.

This paper performs M-GWAS on a Chinese cohort to identify genetic contributions to the gut microbiome and its associations with complex diseases.

This study identifies age-related sex differences in gut microbiota composition and functionality across two population cohorts, showing women have more diverse and stable microbiota than men, with sex differences diminishing in older adults.

The paper analyzes single-cell RNA-seq data from human embryos to compare gene expression between males and females, identifying differences in sex chromosome activation and dosage compensation during early development.

This paper introduces stLFR, a low-cost method for long DNA sequencing that enables accurate variant calling, haplotyping, and de novo assembly.

MetaPGN constructs and visualizes pangenome networks from microbial genomes or metagenomes, revealing genetic diversity in E. coli and gut microbiomes.

This study uses single-cell RNA-seq to analyze the tumor microenvironment of breast cancer, revealing cell type diversity and immune evasion mechanisms.

The paper presents the first draft genome sequence of mandrill, providing a valuable resource for evolutionary and disease research.