Author

Youngkyu Park

Cold Spring Harbor LaboratoryORCID 0000-0003-1169-6739Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Assay:multiome· 1

Frequent Co-Authors

Astrid DeschênesiD· 2 shared David Arthur TuvesoniD· 2 shared Adrian R. KraineriD· 1 shared Alexander J. KraliD· 1 shared Amanda Jensen· 1 shared Benteng MaiD· 1 shared Claudia TonelliiD· 1 shared Ledong WaniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCancer Biology

Astrid DeschênesORCID

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2 papers

Recent·Most cited

Cancer BiologyMolecular Cancer ResearchPeer-reviewedJun 11, 2026

MYC-Driven Activation of USP39 Enhances SRSF1 Stability and Promotes PDAC Progression

Benteng Ma, Xin Zhang, Alexander J. Kral…·Ledong Wan

The paper identifies a MYC-USP39-SRSF1 regulatory axis in PDAC that stabilizes SRSF1 and promotes tumor progression, suggesting USP39 as a therapeutic target.

DOI 10.1158/1541-7786.mcr-25-1104

humanproteomics

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Cancer BiologyCancer ResearchPeer-reviewedApr 2, 2025

Ductal pancreatic cancer interception by FGFR2 abrogation

Claudia Tonelli, Astrid Deschênes, Victoria A. Gaeth…·David Arthur Tuveson

This study identifies FGFR2 as a key driver in early pancreatic tumorigenesis, showing that its inhibition can delay tumor formation and extend survival in mouse models.

11 citationstop 5%

mousehuman

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