Author

Adam Sivitilli

University of Toronto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Bioengineering· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Organism:human· 3 Research Focus:differential expression· 2 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Liliana AttisanoiD· 4 shared Jeffrey L. WranaiD· 3 shared Jessica GosioiD· 3 shared Alesya EvstratovaiD· 2 shared J. Javier HernándeziD· 2 shared Jean‐Martin BeaulieuiD· 2 shared Amin YarmandiD· 1 shared Ana C. AndreazzaiD· 1 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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4 shared papersNeuroscience

Liliana AttisanoORCID

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Author profile →

4 papers

Recent·Most cited

Physiological perfusion of human vasculature reveals a YAP/TAZ-Apelin switch linking intraluminal flow to endothelial state transitions and vessel remodeling

Jian, Tiger, H, Z, Adam Sivitilli, Yaxin E. Guo, Callum Stirton, Jessica Gosio, Yuko Tsukahara, Johnny M. Tkach, Suying Lu, Amin Yarmand, Maria Mangos, Rod Bremner, Jeffrey L. Wrana, Liliana Attisano, Laurence Pelletier

The paper introduces VIVOS, a 3D human vascular platform that links intraluminal flow to endothelial state transitions and vessel remodeling through YAP/TAZ-Apelin signaling.

bioRxiv · Mar 24, 2026 · PreprintBioengineering

Proneural genes define ground state rules to regulate neurogenic patterning and cortical folding

Sisu Han, Satoshi Okawa, Grey Wilkinson, Hussein Ghazale, Lata Adnani, Rajiv Dixit, Lígia Tavares, Imrul Faisal, Matthew J. Brooks, Véronique Cortay, Dawn L. Zinyk, Adam Sivitilli, Saiqun Li, Faizan Malik, Yaroslav Ilnytskyy, , Carol Janine Schuurmans

The paper shows Neurog2 and Ascl1 genes regulate cortical progenitor differentiation and folding through Notch signaling in lissencephalic brains.

Neuron · Aug 17, 2021Peer-reviewedDevelopmental Biology

Characterization of mitochondrial health from human peripheral blood mononuclear cells to cerebral organoids derived from induced pluripotent stem cells

Angela Duong, Alesya Evstratova, Adam Sivitilli, J. Javier Hernández, Jessica Gosio, Azizia Wahedi, Neal Sondheimer, Jeffrey L. Wrana, Jean‐Martin Beaulieu, Liliana Attisano, Ana C. Andreazza

The paper develops cerebral organoids from iPSCs derived from PBMCs to study mitochondrial health across stages and shows preserved mitochondrial function and treatment responses.

Scientific Reports · Feb 25, 2021Peer-reviewedNeuroscience

Robust Production of Uniform Human Cerebral Organoids from Pluripotent Stem Cells

Adam Sivitilli, Jessica Gosio, Bibaswan Ghoshal, Alesya Evstratova, Daniel Trcka, Parisa Ghiasi, J. Javier Hernández, Jean‐Martin Beaulieu, Jeffrey L. Wrana, Liliana Attisano

This study develops a robust method to produce uniform human cerebral organoids with consistent morphology and cell type composition, achieving an 80% success rate.

Life Science Alliance · Apr 17, 2020Peer-reviewedNeuroscience