Eric Blanc

The paper introduces a dual-recombinase system for sequential mutagenesis in germinal center B cells, enabling FOXO1 knockout and subsequent re-expression to study its effects on class switch recombination.

The paper identifies gene dosage effects on telomere maintenance and disease pathways in neuroblastoma using genomic and transcriptomic data from 115 tumors.

The paper develops CCISM to distinguish cancer cells from normal epithelial cells in single-cell data, identifying a novel stem-like cell state in the colorectal cancer microenvironment.

This study identifies Arl8b as a potential biomarker for Alzheimer's disease by analyzing proteomic changes in 5xFAD mouse brain regions and CSF from AD patients.

The paper identifies and ranks recurrent neo-epitopes in cancer using TCGA data and MHC class I binding prediction to prioritize candidates for immunotherapy.

WiPP improves GC-MS peak detection by combining multi-algorithm results with machine learning-based quality assessment, enhancing accuracy and enabling algorithm comparison.

The paper shows that Neurexin and Neuroligin adhesion complexes drive axonal arborisation growth without requiring synaptic activity.

This paper identifies GATA transcription factors that regulate the effects of dietary restriction and TOR signaling on lifespan in Drosophila, showing tissue-specific manipulation can decouple longevity from fitness costs.