Jacopo Marchi

The paper shows that sporulation in B. subtilis reduces phage plaque size by creating spore-rich rings that block phage access to susceptible cells.

This study shows that macrophages reduce bacteriophage density in the lungs, limiting the effectiveness of phage therapy in treating Pseudomonas aeruginosa pneumonia.

The paper shows how spatial interactions enable stable coexistence and transport of virulent phages with migrating bacteria, using theory, simulation, and experiments across multiple systems.

This study uses computational models to show that phage cocktails targeting different bacterial receptors improve treatment outcomes in immunocompromised hosts and reduce resistance evolution.

This study uses a spatially structured metapopulation model and in vivo experiments to evaluate how lung anatomy and immune responses affect the efficacy of phage therapy for Pseudomonas aeruginosa infections.