Author

Patrick M. Lombardi

Mount St. Mary's UniversityORCID 0000-0003-1192-7883Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:multiome· 1 Approach:statistical model· 1

Frequent Co-Authors

Ajin Park· 1 shared Chun‐Kan CheniD· 1 shared Elizabeth A. PollinaiD· 1 shared Hua SuniD· 1 shared Jennifer Olabode· 1 shared Joshua R. BrickneriD· 1 shared Miaw-Sheue TsaiiD· 1 shared Nima MosammaparastiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Ajin Park

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1 paper

Recent·Most cited

YTHDC1 cooperates with the THO complex to prevent RNA damage-induced DNA breaks

Ning Tsao, Patrick M. Lombardi, Ajin Park, Jennifer Olabode, Rebecca Rodell, Hua Sun, Shilpa Padmanaban, Joshua R. Brickner, Miaw-Sheue Tsai, Elizabeth A. Pollina, Chun‐Kan Chen, Nima Mosammaparast

This study shows that RNA damage can cause DNA breaks through R-loop formation, and YTHDC1-THOC prevents this by binding to m1A-modified RNAs.

bioRxiv · Mar 14, 2024Molecular Biology