Author
Lawrence Berkeley National LaboratoryORCID 0000-0003-3239-5724Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Briana H. Greer, Javier Mendia-García, E.A. Mullins…·Brandt F. Eichman
This study reveals how SCFFBH1 promotes fork reversal and regulates RAD51 through DNA binding and ubiquitination, using cryo-EM structures and in vitro experiments.
Mihyun Kim, Eunwoo Jeong, Jiyoung Park…·Orlando D. Schärer
This study investigates the role of XPG interactions with TFIIH subunits p62 and XPD in nucleotide excision repair, showing their importance for catalytic activity and incision initiation.
Mohamed E. Ashour, Ellie Krekeler, Monika Chandan Bhowmik…·Nima Mosammaparast
The paper shows that MutL activates MPG to generate alkylation damage, contributing to cytotoxicity in MMS treatment.
Andrew S. Arvai, Ke Cong, Xiao-Feng Zheng…·Aleem Syed
The paper determines the first high-resolution crystal structures of CDK5-cyclin B1, revealing its mitotic activation mechanism similar to CDK1-cyclin B1.
Ning Tsao, Patrick M. Lombardi, Ajin Park…·Nima Mosammaparast
This study shows that RNA damage can cause DNA breaks through R-loop formation, and YTHDC1-THOC prevents this by binding to m1A-modified RNAs.