Author

Zhizhuo Zhang

Broad InstituteORCID 0000-0003-1202-4037Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:Bayesian inference· 1 Approach:machine learning (classical)· 1 Research Focus:protein design· 1 Assay:protein sequence· 1 Approach:simulation· 1 Approach:statistical model· 1

Frequent Co-Authors

Alan S.L. WongiD· 1 shared Boyue WangiD· 1 shared Claudia C. Wehrspaun· 1 shared Dianbo LiuiD· 1 shared Eva Maria NovoaiD· 1 shared Gigi C.G. ChoiiD· 1 shared Jicong CaoiD· 1 shared Jie FuiD· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperSynthetic Biology

Alan S.L. WongORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintNov 6, 2023

Sample-efficient Antibody Design through Protein Language Model for Risk-aware Batch Bayesian Optimization

Yanzheng Wang, Boyue Wang, Tianyu Shi…·Zhizhuo Zhang

This paper proposes a risk-aware antibody design framework using protein language models and Bayesian optimization, showing improved efficiency and sequence quality over existing methods.

2 citations

protein sequencemachine learning (classical)

𝕏 PostBluesky

Synthetic BiologyNature CommunicationsPeer-reviewedJul 6, 2021

High-Throughput 5' UTR Engineering for Enhanced Protein Production in Non-Viral Gene Therapies

Jicong Cao, Eva Maria Novoa, Zhizhuo Zhang…·Timothy K. Lu

This study develops a high-throughput method to engineer 5' UTRs that enhance protein expression in non-viral gene therapies, identifying synthetic 5 UTRs that outperform existing plasmids.

161 citationstop 1%

statistical modelsimulation

𝕏 PostBluesky